Skin Manifestations and Vascular Endothelial Growth Factor Levels in POEMS Syndrome

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Skin manifestations and vascular endothelial growth factor levels in POEMS syndrome: impact of autologous hematopoietic stem cell transplantation.

OBJECTIVES To investigate skin manifestations of the polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and their correlation with serum vascular endothelial growth factor (s-VEGF-A) levels and to describe the impact of autologous peripheral blood stem cell transplantation (aPBSCT) on these manifestations and the correlation with s-VEGF-A leve...

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Monitoring of Vascular Endothelial Growth Factor in POEMS Syndrome

POEMS syndrome is a clinical unit with a very heterogenous clinical behavior. Its diagnostics as well as monitoring are not easy and depend on clinician ́s experience. We present three case reports of patients with POEMS syndrome with different clinical manifestation and course of the disease. Our presentation demonstrates the benefit of the use of biochemical parameter VEGF (vascular endothelia...

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The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome.

The POEMS syndrome is associated with elevated vascular endothelial growth factor (VEGF) levels. Several studies have compared serum VEGF levels between POEMS patients and other disease entities showing higher serum VEGF in POEMS syndrome; however, it is unknown whether serum levels are reliable and reproducible given variable platelet release of VEGF. We therefore compared plasma levels of VEG...

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ژورنال

عنوان ژورنال: Archives of Dermatology

سال: 2010

ISSN: 0003-987X

DOI: 10.1001/archdermatol.2010.100